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专家介绍
姓    名:
曹勇军
最高学历:
博士
性    别:
科    室:
神经内科
教学职称:
副教授
行政职务:
科副主任
卫生职务:
主任医师
导师类别:
博士生导师
专家门诊:
周一全天,周三上午高级门诊
擅长疾病
临床专业特长:1、擅长脑血管病的规范化诊疗:包括脑血管病急性期溶栓治疗、重症脑血管病综合救治、脑血管病病因及危险因素筛查与干预等;2、神经系统少见、疑难疾病诊治。
基础研究方向:脑缺血再灌注损伤和脑动脉粥样硬化发病机制研究。重点关注纤维蛋白原、氧化低密度脂蛋白、糖基化终产物、硫化氢、自噬及放射性损伤与脑动脉粥样硬化的关系。
主要业绩:率领卒中团队坚持脑血管病临床诊疗特色,在刘春风教授领导下,主持完成了首个长期口服降纤治疗在缺血性脑卒中二级预防中的作用多中心临床研究,该研究获邀在20109月瑞士日内瓦举办的第14届欧洲神经病学学会联盟年会(EFNS)口头交流,引起国际同行的关注。2007年开展静脉溶栓, 2008年组建介入团队,2010年成立苏南首家规范化卒中病房,是江苏省首批能全面开展脑血管病介入诊疗的资质单位之一,在卒中管理和综合救治能力方面有较高的区域影响力。在脑血管病卒中单元建设与管理、神经介入及超急性期动静脉溶栓、长期降纤治疗的临床探索以及放疗后脑动脉狭窄的预后评估等方面有较深入研究。在悉尼大学乔治研究院学习期间,参与INTERACTENCHANTEDSAVE等国际多中心临床研究的数据管理,主持参与国家自然基金项目3项;发表论文200余篇,其中SCI收录45篇。
个人简介
学习简历
1996.07
:安徽医科大学临床医学专业;
2001.07
:获兰州大学医学硕士学位;
2007.06
:获苏州大学医学博士学位。
工作简历
2001.08-2004.08
:东南大学医学院附属马鞍山市人民医院神经内科;
2007.08-----
至今:苏州大学附属第二医院神经内科;
2009.09-2009.12
:北京天坛医院卒中单元进修学习;
2015.04-2016.05:澳大利亚悉尼大学附属乔治研究院(TGI)及皇家阿弗莱德王子医院(RPAH)访问学者。
学术任职

中国卒中学会第一届青年理事会常务理事;

中国研究型医院学会神经科学专业委员会委员;

中国颅脑超声学会全国委员;

中国中西医结合学会眩晕分会青年委员;

江苏省卒中学会常务委员、省医学会脑卒中分会委员;

江苏省神经病学会青委会委员、脑病委员会委员、省脑血管病学组秘书;

苏州市神经病学分会副主任委员、青委会主任委员、脑血管病学组组长;

国家自然科学基金同行评审专家;

教育部研究生学位论文评审专家;

《国际脑血管病杂志》通讯编委;

Stroke & Vascular Neurology》审稿人。

科研情况
1.         论文“the Effects of Antiplatelet Agents on Platelet-leukocyte Aggregations in Patients with Actue Cerebral Infarction”获2008-2009年度“苏州市自然科学优秀学术论文一等奖”;(排名第1
2.         临床研究“检测急性缺血性脑卒中患者中血小板-白细胞聚集体的变化:评价血小板活化的敏感指标”获2007-2008年度“苏州市新技术引进一等奖以及江苏省卫生厅新技术引进二等奖”;(均排名第1
3.         2009年获天坛国际脑血管会议颁发的“BI中国卒中研究奖”1次;(全国共3人)
4.         2014-2015年度“苏州大学以及江苏省优秀硕士学位论文”指导老师。
学术论文&在研项目

 

 

1. Yong-Jun Cao?, Yin-Ming Wang,Chun-Feng Liu?.The effects of antiplatelet agents on platelet-leukocyte aggregations in patients with actue cerebral infarction.J Thromb Thrombolys.2009,27:233-238.(4区,IF:2.039)
2. Xia Zhang,Guo-Dong Xiao,Xing-Shun Xu,Chun-Yuan Zhang,Chun-Feng Liu,Yong-Jun Cao*.A case report and DSA fndings of cerebral hemorrhage caused by syphilitic vasculitis.Neurol Sci.2012,33(6):1411-1414.(Corresponding author;4区,IF:1.495)
3. Xiao G,Sun T,Songming C,Cao Y.NR4A1 enhances neural survival following oxygen and glucose deprivation: An in vitro study.J Neurol Sci.2013,330(1-2) :78-84.(Corresponding author;3区,IF:2.262)
4. Yongjun Cao,Xiaomei Zhou,Huihui Liu,Yanlin Zhang,Xiaoyan Yu,Chunfeng Liu.The NF-?B pathway:regulation of the instability of atherosclerotic plaques activated by Fg, Fb, and FDPs.Mol Cell Biochem.2013;383:29-37.(4区,IF:2.388)
5. Yongjun Cao,Xia Zhang,Chunfeng Liu,et al.Oral fibrinogen-depleting agent lumbrokinase for secondary ischemic stroke prevention: results from a multicenter, randomized, parallel-group and controlled clinical trial.Chin Med J. 2013;126 (21) :4060-4065.(4区,IF:1.016)
6. Xu J,Cao Y. Radiation-induced carotid artery stenosis: a comprehensive review of the literature. Interv Neurol. 2014; 2(4):183-192. (Corresponding author)
7. Xiao-Mei Zhou, Yong-Jun Cao, Gui-Zhen Ao, Li-Fang Hu, Hui Liu, jian Wu, Xiao-Yu Wang, Meng-meng Jin, Shu-Li Zheng, Xue-Chu Zhen, Nabil J. Alkayed, Jia Jia, jian Cheng. CaMKKβ-dependent activation of AMP-activated kinase is critical to suppressive effects of hydrogen sulfide on neuroinflammation. Antioxidants & Redox Signaling. 2014;21(12):1741-1758.(First co-author;2区,IF:7.667)
8. Zhang X, Huang ZC, Lu TS, You SJ, Cao YJ, Liu CF. Prognostic significience of uric acid levels in ischemic stroke patients. Neurotox Res. 2016;29(1):10-20.(Corresponding author;3区,IF:3.538)
9. Xu JP, Shi JJ, Xiao GD, Duan GX, Zhang CY, Cao YJ.Endovascular Treatment of a Distal C1 Dissecting Aneurysm in a Patient with Double Aortic Arch.Chin Med J. 2016;129(1) :112-113.(Corresponding author;4区,IF:1.016)
10. Yan-lin Zhang,Juan-juan Sun,Xiao-yan Yu,Yong-jun Cao. SIRT1 regulates accumulation of oxidized LDL in HUVEC via the autophagy-lysosomal pathway. Prostaglandins & Other Lipid Mediators. 2016122:37-44.(Corresponding author;3区,IF:2.377)
11. You SJ, Han Q, Xu JP, Zhong CK, Zhang Y, Liu HH, Zhang YL, Xu XS, Liu CF,Cao YJ*. Serum Calcium and Phosphate Levels and Short- and Long-Term Outcomes in Acute Intracerebral Hemorrhage Patients. J Stroke Cerebrovasc Dis.201625(4) :914-920.(Corresponding author;4区,IF:1.669)
12. Duan G, Xu J, Shi J, Cao Y. Advances in the pathogenesis, diagnosis and treatment of bow hunter's syndrome: a comprehensive review of the literature. Interv Neurol. 2016; 5(1-2):29-38.Corresponding author)
13. Anderson CS, Robinson T, Lindley RI, Arima H, Lavados PM, Lee TH,Broderick JP, Chen X, Chen G, Sharma VK, Kim JS, Thang NH, Cao Y, Parsons MW, Levi C, Huang Y, Olavarria VV, Demchuk AM, Bath PM,Donnan GA, Martins S, Pontes?Neto OM, Silva F, Ricci S, Roffe C,Pandian J, Billot L, Woodward M, Li Q, Wang X, Wang J, and Chalmers J, for the ENCHANTED Investigators and Coordinators. Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke. N Engl J Med. 2016 ;374(24):2313-2323. (1区,IF:55.873)
14. Yongjun Cao, Xia Wang , Danni Zheng, Thompson Robinson, Daqing Hong, Sarah Richtering, Tzen Hugh Leong, Abdul Salam, Craig AndersonMaree L.ackett. Air Pressure, Humidity and Stroke Occurrence: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health.2016 Jul 5;13(7). pii: E675. doi: 10.3390/ijerph13070675. [Epub ahead of print] (3区,IF:2.063)
15. Xia Wang, Yongjun Cao, Daqing Hong, Danni Zheng, Sarah Richtering, Else Charlotte Sandset, Tzen Hugh Leong, Hisatomi Arima, Shariful Islam, Abdul Salam, Craig Anderson, Thompson Robinson, Maree L. Hackett. Ambient Temperature and Stroke Occurrence:A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2016 Jul 12;13(7). pii: E698. doi: 10.3390/ijerph13070698 [Epub ahead of print] Corresponding author;3区,IF:2.063)
16. You S, Zhong C, Xu J, Han Q, Zhang X, Liu H, Zhang Y, Shi J, Huang Z, Xiao G, Zhang C, Cao Y, Liu C. LDL-C/HDL-C ratio and risk of all-cause mortality in patients with intracerebral hemorrhage. Neurol Res. 2016;14:1-6.Corresponding author;4区,IF:1.418)
17. You S, Shi L, Zhong C, Xu J, Han Q, Zhang X, Liu H, Zhang Y, Shi J, Huang Z, Cao Y, Liu C.Prognostic Significance of Estimated Glomerular Filtration Rate and Cystatin C in Patients with Acute Intracerebral Hemorrhage. Cerebrovasc Dis. 201642(5-6):455-463. (Corresponding author;2区,IF:3.359)
18. You S, Zhong C, Zheng D, Xu J, Zhang X, Liu H, Zhang Y, Shi J, Huang Z, Cao Y, LiuCF.Monocyte to HDL cholesterol ratio is associated with discharge and 3-month outcome in patientswith acute intracerebral hemorrhage. J Neurol Sci. 2017372:157-161. (Corresponding author;3区,IF:2.295)
19. Sun Y, You S, Zhong C, Huang Z, Hu L, Zhang X, Shi J, Cao Y, Liu CF. Neutrophil to lymphocyte ratio and the hematoma volume and stroke severity in acute intracerebral hemorrhage patients. Am J Emerg Med. 2017; 35(3):429-433. [Epub ahead of print] Corresponding author;4区,IF:1.504)
20. You S, Shi L, Zhong C, Du H, Zhang Y, Zheng D,Wang X, Qiu C, Zhao H, Cao Y, Liu C. Admission Low Magnesium Level Is Associated with In-Hospital Mortality in Acute Ischemic Stroke Patients. Cerebrovasc Dis. 201744(1-2):35-42. (Corresponding author;2区,IF:3.359)
21. Shi J, Cao Y, You S, Huang Z, Zhang X, Liu H, Liu CF. Yong stroke patients treated with intravenous thrombolysis have a more favorable outcome and mortality compared with order patients. Curr Neurovasc Res. 201714:141-148.(Corresponding author;3区,IF:2.123)
22. Bei HZ, You SJ, Zheng D, Zhong CK, Du HP, Zhang Y, Lu TS, Cao LD, Dong XF, Cao YJ.Liu CF. Prognostic role of hypochloremia in acute ischemic stroke patients. Acta Neurol Scand. 2017doi: 10.1111/ane.12785. [Epub ahead of print] (Corresponding author;3区,IF:3.087)
23. You S, Yin X, Liu H, Zheng D, Zhong C, Du H, Zhang Y, Zhao H, Qiu C, Fan L, Pei S, Ma Z, Cao Y, Liu CF. Hyperfibrinogenemia and in-hospital mortality in acute ischemic stroke patients.Curr Neurovasc Res. 201714(3):242-249.(Corresponding author;3区,IF:2.123)
24. Xu JP, Shi JJ, Duan GX, Cao YJ. Imaging Features of Symptomatic Radiation-induced Cervical Artery Stenosis. Chin Med J. 2017130:1876-1877. (Corresponding author;4区,IF:1.064)
25. You S, Zheng D, Zhong C, Wang X, Tang W, Sheng L, Zheng C, Cao Y, Liu CF. Prognostic Significance of Blood Urea Nitrogen in Acute Ischemic Stroke. Circ J. 2017. doi: 10.1253/circj.CJ-17-0485. [Epub ahead of print] Corresponding author;2区,IF:3.544)
26. Sun JJ, Yin XW, Liu HH, Du WX, Shi LY, Huang YB, Wang F, Liu CF, Cao YJ, Zhang YL.Rapamycin inhibits ox-LDL-induced inflammation in human endothelial cells in vitro by inhibiting the mTORC2/PKC/c-Fos pathway. Acta Pharmacol Sin. 2017 Oct 26. doi: 10.1038/aps.2017.102. [Epub ahead of print] Corresponding author;3区,IF:3.223)